中文
Short name：NGAL
Detection method：Latex enhanced immunoturbidimetry
Packaging specifications：Various
①: The product packaging is suitable for mainstream models such as Hitachi, Abbott, Siemens, Roche, Beckman, Toshiba, Deere, Mindray, Kehua and so on.
②: High sensitivity, high specificity and strong anti-interference ability.
Clinical Significance
The molecular weight of NGAL is about 25kDa, covalently bound to the cglocyte gelatinase. In physiological state, NGAL is a growth factor, which is mainly involved in the development and growth of early renal epithelium. The expression was low in the epithelium of normal tissues including kidney, lung, stomach and colon. In the course of ischemic and toxic renal injury, NGAL levels in renal tubular epithelial cells are significantly increased, so NGAL is a sensitive marker of early acute renal injury and a marker of renal function injury. It is suitable for the detection of chronic nephropathy (CKD), diabetic nephropathy, lupus nephropathy, IgA tubular interstitial injury, cardio-renal syndrome (CRS), etc.
Inspecting Principle
The NGAL in the sample reacts with the hypersensitive anti-ngal antibody latex granules to form an immune complex. The turbidity change is a function of the NGAL concentration in the sample.
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